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https://open.uns.ac.rs/handle/123456789/9989
Title: | Cloning of the genes for non-medullary thyroid cancer: Methods and advances | Authors: | Stankov, Karmen Romeo G. |
Issue Date: | 1-Jan-2006 | Journal: | Archive of Oncology | Abstract: | In last ten years, significant advances have occurred in thyroid endocrinology, as a consequence of the generalized use of molecular biology techniques. New genes involved in the development of thyroid cancer have been identified, which had a great impact on our understanding of thyroid cancer predisposition. All cancers are genetic in origin because they arise from mutations in a single somatic cell, but the genetic changes in sporadic cancers are confined to a particular tissue. In inherited cancers, a predisposing mutation is present in all somatic cells and in the germ line, which enables the transmission of risk to the next generation. Cancer genetics offers a model of how information on the genetics of inherited cancers could affect identification of individuals at increased genetic risk. © 2006, Institute of Oncology Sremska Kamenica. | URI: | https://open.uns.ac.rs/handle/123456789/9989 | ISSN: | 3547310 | DOI: | 10.2298/AOO0602030S |
Appears in Collections: | MDF Publikacije/Publications |
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