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https://open.uns.ac.rs/handle/123456789/5251
Title: | Radial endobronchial ultrasound (EBUS) Guided suction catheter-biopsy in histological diagnosis of peripheral pulmonary lesions | Authors: | Bojan Zarić Vladimir Stojšić Vladimir Čarapić Tomi Kovačević Goran Stojanović Milana Panjković Kioumis I. Darwiche K. Zarogoulidis K. Stratakos G. Tsavlis D. Hohenforst-Schmidt W. Pitsiou G. Zissimopoulos A. Sachpekidis N. Karapantzos I. Karapantzou C. Zarogoulidis P. Branislav Perin |
Keywords: | bronchoscopy;endobronchial ultrasound EBUS;interventional pulmonology;lung cancer;peripheral pulmonary lesion | Issue Date: | 1-Jan-2016 | Journal: | Journal of Cancer | Abstract: | © 2015 AIP Publishing LLC. Background: EBUS guided trans-bronchial biopsy became routine in diagnosis of peripheral pulmonary lesions (PPL). Suction catheter-biopsy is a technique for obtaining a tissue sample from peripheral lung parenchyma. Aim of this study was to evaluate diagnostic efficiency, feasibility and safety of EBUS guided suction catheter-biopsy (SCB) in comparison to trans-bronchial biopsy (TBB) in diagnosis of PPL. The main intention was to demonstrate non-inferiority of the technique over trans-bronchial biopsy, especially when used under navigation of the EBUS. Methods: Radial EBUS probe (UM-3R, Olympus Co, Japan.) without guiding sheath was used to navigate suction catheter and TBB forceps to the PPL. The catheter was connected to the collection canister via vacuum pump. The SCB specimens were fixed with 10% buffered formalin. Results: There were 168 patients enrolled in this study; 69.9% males and 30.1% females. Main lesion diameter was 4.1±1.9 cm. Majority of patients, 131(77.9%) were diagnosed with lung cancer. Per-biopsy calculated sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for EBUS-SCB were 92.4%, 100%, 100% and 67.7%, respectively. Corresponding values for EBUS-TBB were 92.3%, 100%, 100% and 69.7%. Only the size of the lesion significantly influenced (p=0.005) diagnostic performance. Complications occurred in 2 patients; one pneumothorax and one excessive bleeding. Conclusion: EBUS guided SCB is efficient, feasible and safe in diagnosis of peripheral lung cancer. The technique is complementary to trans-bronchial biopsy. | URI: | https://open.uns.ac.rs/handle/123456789/5251 | DOI: | 10.7150/jca.13081 |
Appears in Collections: | FTN Publikacije/Publications |
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