Retention behaviour of 1,6-anhydrohexose and D-aldopentose derivatives on silica gel thin layers

Abstract

To study the relation between the chemical structure of solutes and their retention behaviour in thin layer chromatography on silica gel, the retention constant (R M value) of a series of variously substituted 1,6-anhydrohexose and D-aldopentose derivatives were measured as a function of the composition of eight non-aqueous binary eluents. The slopes and intercepts of the linear relations between the retention constants (R M ) and the logarithm of the volume fraction of the stronger eluent component have been calculated applying in adsorption chromatography well-known Soczewinski equation and discussed in relation to the solute and eluent characteristics.