Please use this identifier to cite or link to this item: https://open.uns.ac.rs/handle/123456789/16315
Title: Optimization of Hybrid Microfluidic Chip Fabrication Methods for Biomedical Application
Authors: Kojić, Sanja 
Birgermajer, Slobodan 
Radonić, Vasa 
Podunavac, Ivana 
Jevremov, Jovana
Petrović, Bojan 
Marković, Evgenija
Stojanović, Goran 
Keywords: microfluidic fabrication;3D printing;xurography;optimization;characterization;NiTi archwire
Issue Date: Aug-2020
Publisher: Springer
Project: SALSETH
Journal: Microfluidics and Nanofluidics
Abstract: Microfluidic chips have become attractive devices with enormous potential for a wide range of applications. The optimal performances of microfluidic platforms cannot be achieved using a single fabrication technique. The method of obtaining the dominant characteristic of a microfluidic chip is to combine the best qualities of different technological processes and materials. In this paper, we propose a novel, cost-effective, hybrid microfluidic chip manufacturing technologies that combine 3D printing process and xurographic technique. The standard Y-mixer was 3D printed using thermoplastic polymers, while the enclosure of the channel was achieved using the PVC lamination foils. The influence of the fabrication parameters, materials and bonding layers on the channel dimensions, performances and durability in the process of chip realization have been analysed and tested. Optimized parameters have been established for 3D fabrication process. The potential application in biomedicine and material science has been demonstrated on the example with nickel-titanium (NiTi) orthodontic archwire
URI: https://open.uns.ac.rs/handle/123456789/16315
ISSN: 1613-4982
DOI: https://doi.org/10.1007/s10404-020-02372-0
Rights: Attribution-NonCommercial-NoDerivs 3.0 United States
Appears in Collections:FTN Publikacije/Publications
IBS Publikacije/Publications

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