Молимо вас користите овај идентификатор за цитирање или овај линк до ове ставке:
https://open.uns.ac.rs/handle/123456789/11657
Назив: | Evaluation and validation of two chromatographic methods (HPLC-Fluorescence and LC-MS/MS) for the determination and confirmation of ochratoxin A in pig tissues | Аутори: | Milićević, Dragan Jurić, Verica Stefanović, Srđan Baltić, Tatjana Jankov, Saša |
Датум издавања: | 1-мај-2010 | Часопис: | Archives of Environmental Contamination and Toxicology | Сажетак: | Two different analytical methods for the determination and confirmation of ochratoxin A (OTA) in blood serum, kidney, and liver of pigs have been compared. Sample cleanup was based on liquid-liquid phase extraction. The detection of OTA was accomplished with high-performance liquid chromatography (HPLC) combined either with fluorescence detection (FLD) or electrospray ionization (ESI+) tandem mass spectrometry (MS/MS). The comparative method of evaluation was based on the investigation of 90 samples of blood serum, kidney, and liver per animal originating from different regions of Serbia. The analytical results are discussed in view of the respective method validation data and the corresponding experimental protocols. In general, analytical data obtained with liquid chromatography (LC)-MS/MS detection offered comparable good results in the sub-ppb concentration level indicating that the electrospray tandem mass spectrometric (LC-MS/MS) method was more selective and sensitive for the analysis and confirmation of OTA in pig tissues than the HPLC method after the methylation of OTA. © 2009 Springer Science+Business Media, LLC. | URI: | https://open.uns.ac.rs/handle/123456789/11657 | ISSN: | 00904341 | DOI: | 10.1007/s00244-009-9436-2 |
Налази се у колекцијама: | POLJF Publikacije/Publications |
Приказати целокупан запис ставки
SCOPUSTM
Навођења
15
проверено 15.03.2024.
Преглед/и станица
34
Протекла недеља
10
10
Протекли месец
0
0
проверено 03.05.2024.
Google ScholarTM
Проверите
Алт метрика
Ставке на DSpace-у су заштићене ауторским правима, са свим правима задржаним, осим ако није другачије назначено.