Молимо вас користите овај идентификатор за цитирање или овај линк до ове ставке:
https://open.uns.ac.rs/handle/123456789/7923
Назив: | Acetylcholinesterase inhibitory, antioxidant and phytochemical properties of selected medicinal plants of the lamiaceae family | Аутори: | Sanda Vladimir Knežević Blazekovic B. Kindl M. Vladić, Jelena Lower-Nedza A. Brantner A. |
Датум издавања: | 1-јан-2014 | Часопис: | Molecules | Сажетак: | The present study aimed to evaluate acetylcholinesterase (AChE) inhibitory and antioxidant activities of Lamiaceae medicinal plants growing wild in HRV. Using Ellman's colorimetric assay all tested ethanolic extracts and their hydroxycinnamic acid constituents demonstrated in vitro AChE inhibitory properties in a dose dependent manner. The extracts of Mentha x piperita, M. longifolia, Salvia officinalis, Satureja montana, Teucrium arduini, T. chamaedrys, T. montanum, T. polium and Thymus vulgaris at 1 mg/mL showed strong inhibitory activity against AChE. The antioxidant potential of the investigated Lamiaceae species was assessed by DPPH scavenging activity and total antioxidant capacity assays, in comparison with hydroxycinnamic acids and trolox. The extracts differed greatly in their total hydroxycinnamic derivatives content, determined spectrophotometrically. Rosmarinic acid was found to be the predominant constituent in most of the investigated medicinal plants (by RP-HPLC) and had a substantial influence on their AChE inhibitory and antioxidant properties, with the exception of Teucrium species. These findings indicate that Lamiaceae species are a rich source of various natural AChE inhibitors and antioxidants that could be useful in the prevention and treatment of Alzheimer's and other related diseases. | URI: | https://open.uns.ac.rs/handle/123456789/7923 | DOI: | 10.3390/molecules19010767 |
Налази се у колекцијама: | TF Publikacije/Publications |
Приказати целокупан запис ставки
SCOPUSTM
Навођења
176
проверено 10.05.2024.
Преглед/и станица
27
Протекла недеља
9
9
Протекли месец
0
0
проверено 10.05.2024.
Google ScholarTM
Проверите
Алт метрика
Ставке на DSpace-у су заштићене ауторским правима, са свим правима задржаним, осим ако није другачије назначено.