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https://open.uns.ac.rs/handle/123456789/7134
Nаziv: | Bioactivity of Meeker and Willamette raspberry (Rubus idaeus L.) pomace extracts | Аutоri: | Četojević-Simin, Dragana Ranitović (Velićanski), Aleksandra Cvetković, Dragoljub Markov, Siniša Ćetković, Gordana Tumbas Šaponjac, Vesna Vulić, Jelena Čanadanović-Brunet, Jasna Đilas, Sonja |
Dаtum izdаvаnjа: | 1-јан-2015 | Izdаvаč: | Elsevier | Čаsоpis: | Food Chemistry | Sažetak: | Taking into account the substantial potential of raspberry processing by-products, pomace extracts from two raspberry cultivars, Meeker and Willamette, were investigated. Total phenolic, flavonoid and anthocyanin contents were determined. Willamette pomace extract (EC50 = 0.042 mg/ml) demonstrated stronger 2,2-diphenyl-1-picrylhydrazyl DPPH radical-scavenging activity than did Meeker pomace extract (EC50 = 0.072 mg/ml). The most pronounced cell growth inhibition effect was obtained in the breast adenocarcinoma cell line, reaching EC50 values of 34.8 and 60.3 μg/ml for Willamette and Meeker extracts, respectively. Both extracts demonstrated favourable non-tumor/tumor cell growth ratios and potently increased the apoptosis/necrosis ratio in breast adenocarcinoma and cervix carcinoma cells. In reference and wild bacterial strains, minimal inhibitory concentrations (MIC) were achieved in a concentration range from 0.29 to 0.59 mg/ml, and minimal bactericidal concentrations (MBC) in a range from 0.39 to 0.78 mg/ml. The results indicate significant antioxidant, antiproliferative, proapoptotic and antibacterial activities of raspberry pomace and favour its use as a functional food ingredient. © 2014 Elsevier Ltd. All rights reserved. | URI: | https://open.uns.ac.rs/handle/123456789/7134 | ISSN: | 03088146 | DOI: | 10.1016/j.foodchem.2014.06.063 |
Nаlаzi sе u kоlеkciјаmа: | TF Publikacije/Publications |
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