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https://open.uns.ac.rs/handle/123456789/6878
Title: | Clinical and microbiological effects of the initial periodontal therapy | Authors: | Predin T. Djurić M. Mirnić, Jelena Gušić, Ivana Nikolić, Nebojša Marković, Đorđe Andjelković A. Milašin J. |
Issue Date: | 1-Jan-2014 | Journal: | Srpski Arhiv za Celokupno Lekarstvo | Abstract: | Introduction Periodontitis is a destructive inflammatory disease of the tooth-supporting tissues, primarily caused by Gram-negative microorganisms. Thus, the primary objective of cause-related initial periodontal therapy is disruption and removal of the subgingival biofilm. Objective The aim of this study was to evaluate the clinical and microbiological effects of the initial therapy in patients diagnosed with chronic periodontitis. Methods Forty patients with chronic periodontitis were included in the study. As a part of the clinical assessment undertaken prior to the initial therapy, as well as one month and three months post-therapy, plaque index, gingival index, papilla bleeding index, probing pocket depth and clinical attachment level were recorded. Microbiological testing was performed prior to the initial therapy and three months after therapy. Polymerase chain reaction assays were used to determine the presence of Porphyromonas gingivalis, Tannerella forsythensis, Prevotella intermedia and Aggregatibacter actinomycetemcomitans. Results All clinical parameters were significantly reduced after therapy. The prevalence of Aggregatibacter actinomycetem-comitans was reduced by 22.5%, which was a statistically significant decrease compared to the baseline. The prevalence of Porphyromonas gingivalis, Tannerella forsythensis and Prevotella intermedia tended to decrease after therapy; however, the difference did not reach statistical significance. Conclusion The results of the present study demonstrated the beneficial effects of the initial periodontal therapy on both the clinical and microbiological parameters. | URI: | https://open.uns.ac.rs/handle/123456789/6878 | ISSN: | 3708179 | DOI: | 10.2298/SARH1402010P |
Appears in Collections: | MDF Publikacije/Publications |
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