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https://open.uns.ac.rs/handle/123456789/6810
Nаziv: | Acute kidney injury in preterm infants admitted to a neonatal intensive care unit | Аutоri: | Vesna Stojanović Nenad Barišić Borko Milanović Aleksandra Doronjski |
Ključnе rеči: | Acute kidney injury;Risk factors;Fluids;Preterm infant;Neonatal intesive care units | Dаtum izdаvаnjа: | 1-јан-2014 | Čаsоpis: | Pediatric Nephrology | Sažetak: | © 2014, IPNA. Background: The factors that contribute to the development of acute kidney injury (AKI) and treatment outcome among prematurely born neonates are not clearly understood.Methods: This retrospective study included 150 prematurely born neonates. AKI was defined as an increase of serum creatinine levels ≥0.3 mg/dl compared to basal values.Results: The majority of neonates with AKI (94.8 %) had a body weight <1,500 g. Logistic regression analysis showed that the Apgar score in the 5th minute <5, serum lactate levels >5 on the first day of life, core body temperature <36 ºC on the first day of life, occurrence of sepsis, intracranial hemorrhage, necrotizing enterocolitis, patent ductus arteriosus, as well as a treatment with vancomycin or dopamine were independent risk factors for the development of AKI. After the groups of neonates with and without AKI were adjusted, the calculated risk ratio for a negative outcome of treatment (death) was 2.215 (CI 1.27–3.86) for neonates with AKI. Neonates with AKI had higher serum sodium levels in the third and fourth days of life.Conclusions: AKI is associated with high mortality in preterm neonates. It is very important to identify, as quickly as possible, all infants who are at high risk of developing AKI. | URI: | https://open.uns.ac.rs/handle/123456789/6810 | ISSN: | 0931041X | DOI: | 10.1007/s00467-014-2837-0 |
Nаlаzi sе u kоlеkciјаmа: | MDF Publikacije/Publications |
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