Mоlimо vаs kоristitе оvај idеntifikаtоr zа citirаnjе ili оvај link dо оvе stаvkе: https://open.uns.ac.rs/handle/123456789/6796
Nаziv: Dystrophic calcifications and Raynaud's phenomenon in an eight-year old girl
Аutоri: Slobodan Grebeldinger 
Jelena Tomić
Gordana Vijatov Đurić 
Branka Radojčić
Nada Vučković 
Jelena Ćulafić
Ključnе rеči: Raynaud disease;calcinosis;child
Dаtum izdаvаnjа: 1-јан-2014
Čаsоpis: Srpski Arhiv za Celokupno Lekarstvo
Sažetak: Introduction: Dystrophic calcifications are the most common subtype of skin calcinosis. Tumorous soft tissue calcium deposits usually contain hydroxyapatite and amorphous calcium phosphate. Differential diagnosis of skin calcinosis encompasses Thibierge-Weissenbach syndrome, systemic sclerosis, scleroderma, CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia), dermatomyositis, systemic lupus erythematosus, ad myositis ossificans progressiva. Case Outline: We present the case of an eight-year old girl with tumorous soft tissue calcium deposits and Raynaud's phenomenon. At the age of 3.5 years, our patient was admitted to Pediatric Surgery Clinic because of bilateral acrocyanosis localized at the fingertips area of hands, with the signs of vascular trauma. Therapy with vasodilators and hyperbaric oxygen treatment were completed. This therapy resulted in improvement. At the age of eight, the patient was admitted again due to intermittent, painful cramps localized in both hands. Punctiform deposits were present at the tips of fingers and toes, which looked like calcifications and were spontaneously eliminated, with the remnants of crater-shaped defects. A hard tumorous deformity localized in soft tissue was present in the extensor area of the right elbow. Laboratory indicators of inflammation were within the reference values, and antinuclear antibodies were positive. A nodus localized at the right elbow was extirpated. Pathohistological findings: connective and fat tissue with large deposits of calcium. Conclusion: Further follow-up of our patient is necessary due to possible development of complete picture of CREST syndrome or systemic sclerosis.
URI: https://open.uns.ac.rs/handle/123456789/6796
ISSN: 3708179
DOI: 10.2298/SARH1404239G
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