Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/6670
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Vesna Stojanović | en_US |
dc.contributor.author | Nenad Barišić | en_US |
dc.contributor.author | Nada Vučković | en_US |
dc.contributor.author | Aleksandra Doronjski | en_US |
dc.contributor.author | Amira Peco Antić | en_US |
dc.date.accessioned | 2019-09-30T08:56:39Z | - |
dc.date.available | 2019-09-30T08:56:39Z | - |
dc.date.issued | 2015-01-01 | - |
dc.identifier.issn | 313998 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/6670 | - |
dc.description.abstract | © 2015 International Pediatric Research Foundation, Inc. Background:The new urinary and serum biomarkers are discovered and are being investigated. With them we can diagnose acute kidney injury (AKI) faster and more precisely and they also have a significant role in the outcome prediction.Methods:The study included 22 extremely low-birth-weight neonates who were hospitalized in the neonatal intensive care units. They were divided into two groups based on serum creatinine (SCr) level - with and without AKI. Detection and quantification of urinary kidney injury molecule-1 (uKIM-1) was done on the third day of life, using commercially available KIM-1 rapid test. Subsequently, measurements were repeated only in subjects who were diagnosed with AKI, at different values of SCr.Results:Logistic regression analysis showed that AKI is an independent risk factor for mortality. In a group of neonates with AKI, 50% of neonates administered the KIM-1 rapid test showed positive findings. KIM-1 rapid test was positive in patients with a wide range of SCr levels (range of 78.73-385 μmol/l), but all subjects had oliguria and died in the next 24 h.Conclusion:KIM-1 is a significant predictor of death. On the other hand, our study failed to prove that KIM-1 rapid test has any significance for early prediction of AKI. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Pediatric Research | en_US |
dc.subject | biomarkers | en_US |
dc.subject | acute kidney injury | en_US |
dc.subject | outcome prediction | en_US |
dc.subject | extremely low-birth-weight neonates | en_US |
dc.subject | uKIM-1 rapid test | en_US |
dc.title | Urinary kidney injury molecule-1 rapid test predicts acute kidney injury in extremely low-birth-weight neonates | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.doi | 10.1038/pr.2015.125 | - |
dc.identifier.pmid | 78 | - |
dc.identifier.scopus | 2-s2.0-84942918682 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/84942918682 | - |
dc.description.version | Published | en_US |
dc.relation.lastpage | 435 | en_US |
dc.relation.firstpage | 430 | en_US |
dc.relation.issue | 4 | en_US |
dc.relation.volume | 78 | en_US |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Medicinski fakultet, Katedra za pedijatriju | - |
crisitem.author.dept | Medicinski fakultet, Katedra za patologiju | - |
crisitem.author.orcid | 0000-0002-8869-4806 | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
Appears in Collections: | MDF Publikacije/Publications |
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