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https://open.uns.ac.rs/handle/123456789/5842
Nаziv: | Treatment of Periodontal Disease with an Octenidine-based Antiseptic in HIV-positive Patients | Аutоri: | Gušić, Ivana Medić D. Radovanović Kanjuh M. Ethurić M. Brkić, Miodrag Turkulov, Vukan Predin T. Mirnić, Jelena |
Dаtum izdаvаnjа: | 1-мај-2016 | Čаsоpis: | International Journal of Dental Hygiene | Sažetak: | © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. Objective: To evaluate the effects of a periodontal therapy with subsequent application of an octenidine (OCT)-based antiseptic in HIV-positive patients receiving highly active antiretroviral therapy. Methods: HIV-positive patients with a clinically diagnosed periodontal disease were randomly divided into two groups (n = 30/group). Both groups initially received a periodontal therapy. Patients in the OCT group additionally used an OCT-based mouthwash. Subgingival plaque samples and periodontal indices were analysed prior to treatment onset as well as one and 3 months post-treatment. Results: Periodontal therapy has resulted in a significant decrease in the values of all periodontal indices one and 3 months following the therapy completion (P = 0.000). The effects of the two applied therapeutic protocols differed significantly in terms of the variation in the PBI (F = 4.617; P = 0.017) and the PD (F = 3.203; P = 0.044) value. In the patients in the OCT group, a more pronounced decrease in the PBI and PD was noted at 1-month follow-up as well as a greater increase in the PD value 3 months upon treatment completion. In the OCT group, no more atypical microorganisms were detectable 1 month post-treatment, while in the control group they were found in 34.5% of patients. Conclusions: The periodontal therapy bears good results in HIV-positive patients. Additional administration of OCT contributes to the significant decline in the PBI and DS values and eliminates atypical microorganisms within 1 month post-treatment. However, more favourable results were not noted in the OCT group at the 3-month assessment. | URI: | https://open.uns.ac.rs/handle/123456789/5842 | ISSN: | 16015029 | DOI: | 10.1111/idh.12141 |
Nаlаzi sе u kоlеkciјаmа: | MDF Publikacije/Publications |
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