Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/5252
Title: | Drug eluting stents for malignant airway obstruction: A critical review of the literature | Authors: | Hohenforst-Schmidt W. Zarogoulidis P. Pitsiou G. Linsmeier B. Tsavlis D. Kioumis I. Papadaki E. Freitag L. Tsiouda T. Turner J. Browning R. Simoff M. Sachpekidis N. Tsakiridis K. Zarić, Bojan Yarmus L. Baka S. Stratakos G. Rittger H. |
Issue Date: | 1-Jan-2016 | Journal: | Journal of Cancer | Abstract: | © Ivyspring International Publisher. Lung cancer being the most prevalent malignancy in men and the 3rd most frequent in women is still associated with dismal prognosis due to advanced disease at the time of diagnosis. Novel targeted therapies are already on the market and several others are under investigation. However non-specific cytotoxic agents still remain the cornerstone of treatment for many patients. Central airways stenosis or obstruction may often complicate and decrease quality of life and survival of these patients. Interventional pulmonology modalities (mainly debulking and stent placement) can alleviate symptoms related to airways stenosis and improve the quality of life of patients. Mitomycin C and sirolimus have been observed to assist a successful stent placement by reducing granuloma tissue formation. Additionally, these drugs enhance the normal tissue ability against cancer cell infiltration. In this mini review we will concentrate on mitomycin C and sirolimus and their use in stent placement. | URI: | https://open.uns.ac.rs/handle/123456789/5252 | DOI: | 10.7150/jca.13611 |
Appears in Collections: | MDF Publikacije/Publications |
Show full item record
SCOPUSTM
Citations
41
checked on May 3, 2024
Page view(s)
14
Last Week
5
5
Last month
0
0
checked on May 10, 2024
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.