Quality assurance in radiotherapy - verificationof treatment planning system and clinicalimplementation of in vivo dosimetry

Abstract

<p>Predmet istraživanja ove doktorske disertacije<br />je osiguranje kvaliteta u radioterapiji. U okviru<br />rada na disertaciji je sprovedena klinička<br />verifikacija sistema za planiranje terapije u<br />vedim radioterapijskim centrima u Srbiji sa<br />ciljem obezbeđivanja optimalnog kori&scaron;denja<br />TPS i bezbedne radioterapije. Ova verifikacija<br />predstavlja bitan deo QA radioterapijskog<br />procesa, gde se nakon početne verifikacije<br />prikupljeni podaci koriste i za dalje periodične<br />provere u okviru osiguranja kvaliteta. Dalje<br />istraživanje je sprovedeno u cilju<br />implementacije in vivo dozimetrije u kliničku<br />praksu kao veoma bitne procedure za<br />osiguranje kvaliteta čitavog radioterapijskog<br />procesa, od preskripcije do isporuke doze. Na<br />taj način su određeni nivoi tolerancije/akcije za<br />različite grupe pacijenata i određene<br />radioterapijske tehnike. Takođe, procenjena je<br />tačnost radioterapijskog procesa na Institutu za<br />onkologiju Vojvodine u Sremskoj Kamenici.</p>

<p>The subject of this dissertation is quality<br />assurance (QA) in radiotherapy. As part of the<br />thesis was conducted clinical verification of<br />treatment planning systems (TPS) in major<br />radiotherapy centers in Serbia in order to<br />ensure the optimal usage of TPS and safe<br />radiotherapy. This TPS verification is an<br />important part of radiotherapy QA process,<br />where after an initial verification of the data<br />collected and then used for further periodic<br />checks as part of quality assurance. Further<br />research was conducted in order to implement<br />in vivo dosimetry in clinical practice as a very<br />important procedure for quality assurance of<br />the entire radiotherapy process, from<br />prescription to dose delivery. In this way,<br />tolerance/actions levels for different groups of<br />patients and specific radiation technique were<br />determined. Also, the accuracy of the<br />radiotherapy process at the Institute of<br />oncology of Vojvodina in Sremska Kamenica<br />was estimated.</p>