Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/28902
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Đurendić Evgenija | - |
dc.contributor.author | Ajduković Jovana | - |
dc.contributor.other | Penov-Gaši Katarina | - |
dc.contributor.other | Đurendić Evgenija | - |
dc.contributor.other | Sakač Marija | - |
dc.contributor.other | Csanádi János | - |
dc.contributor.other | Đilas Sonja | - |
dc.date.accessioned | 2020-12-14T16:01:11Z | - |
dc.date.available | 2020-12-14T16:01:11Z | - |
dc.date.issued | 2013-10-08 | - |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/28902 | - |
dc.description.abstract | <p>U prvom delu ove doktorske disertacije je izvršena sinteza novih 17α-pikolil i 17(E)-pikoliniliden androstanskih derivata, sa modifikacijama u A- i/ili B-prstenovima. U drugom delu rada je ispitana antiproliferativna aktivnost odabranih novosintetizovanih jedinjenja prema humanim tumorskim ćelijskim linijama (MCF-7, MDA-MB-231, PC-3, HeLa, HT-29 i A549) kao i prema zdravim ćelijama fetalnih fibroblasta pluća (MRC-5).</p> | sr |
dc.description.abstract | <p>In the first part of this dissertation, the synthesis of new 17α-picolyl and 17(E)-picolinylidene androstane derivatives with modifications in A and/or B rings, were presented. The second part of the work consisted on investigation of antiproliferative activity of selected newly synthesized compounds toward human carcinoma cell lines (MCF-7, MDA-MB-231, PC-3, HeLa, HT-29 and A549), as well as the healthy fetal lung fibroblasts (MRC-5).</p> | en |
dc.language.iso | sr (latin script) | - |
dc.publisher | Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu | sr |
dc.publisher | University of Novi Sad, Faculty of Sciences at Novi Sad | en |
dc.source | CRIS UNS | - |
dc.source.uri | http://cris.uns.ac.rs | - |
dc.subject | Synthesis, steroids, androstane derivatives, antiproliferative activity | en |
dc.subject | Sinteza, steroidi, derivati androstana, antiproliferativna aktivnost | sr |
dc.title | Synthesis and biological activity of 17-substituted androstane derivatives | en |
dc.title | Sinteza i biološka aktivnost 17-supstituisanih androstanskih derivata | sr |
dc.type | Thesis | en |
dc.identifier.doi | 10.2298/NS20131008AJDUKOVIC | - |
dc.identifier.url | https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija139151012932947.pdf?controlNumber=(BISIS)85334&fileName=139151012932947.pdf&id=1267&source=BEOPEN&language=en | en |
dc.identifier.url | https://www.cris.uns.ac.rs/record.jsf?recordId=85334&source=BEOPEN&language=en | en |
dc.identifier.externalcrisreference | (BISIS)85334 | - |
dc.source.institution | Prirodno-matematički fakultet u Novom Sadu | sr |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
Appears in Collections: | PMF Teze/Theses |
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