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Назив: CHROMATOGRAPHIC BEHAVIOR AND LIPOPHILICITY OF N-(4-PHENYLSUBSTITUTED)-2,3-DIPHENYLPROPANAMIDES
Аутори: Vaštag Đenđi 
Perišić-Janjić Nada
Apostolov Suzana 
Petrović Slobodan
Кључне речи: N-(4-phenylsubstituted)-2,3-diphenylpropanamides, thin layer chromatography, lipophilicity
Датум издавања: 2011
Часопис: Proceedings 2nd International Congress “Engineering, Ecology and Materials in Processing Industry” (EEM), 2nd International Congress Engineering, Ecology and Materials in the Processing Industry, Jahorina, Bosnia and Herzegovina, 2011, 09.03.-11.03., No 2
Сажетак: Retention behavior of some N-(4-phenylsubstituted)-2,3-diphenylpropanamides was investigated on reversed phase thin layer chromatography(RP-C18). Retention constants of investigated compounds were determined in the following solvent sistems: water-ethanol, water-n-propanol and water-i-propanol. Linear relationships were obtained between retention,RM and volume fraction of organic solvent, . As measure of biological activity of tested acetamides, Hansch`s lipophilicity parameter, π, were calculated. Chromatography retention constants RM0 were correlated with Hansch`s lipophilicity parameter, and very good linear relationships were obtained. The results show that retention constants, (RM0), determined in reversed phase thin-layer chromatography (RP-TCL) can be used, as criteria of its lipophilicity.
URI: https://open.uns.ac.rs/handle/123456789/26896
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