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https://open.uns.ac.rs/handle/123456789/2239
Title: | Human skeletal muscle contains no detectable guanidinoacetic acid | Authors: | Ostojić, Sergej Ostojić, Jelena |
Issue Date: | 6-Feb-2018 | Journal: | Applied Physiology, Nutrition and Metabolism | Abstract: | We analyzed data from previously completed trials to determine the effects of supplemental guanidinoacetic acid (GAA) on markers of muscle bioenergetics in healthy men using 1.5 T magnetic resonance spectroscopy. No detectable GAA (<0.1μmol/L) was found in the vastus medialis muscle at baseline nor at follow-up. This implies deficient GAA availability in the human skeletal muscle, suggesting absent or negligible potential for creatine synthesis from GAA inside this tissue, even after GAA loading. | URI: | https://open.uns.ac.rs/handle/123456789/2239 | ISSN: | 1715-5312 | DOI: | 10.1139/apnm-2017-0873 |
Appears in Collections: | FSFV Publikacije/Publications MDF Publikacije/Publications |
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