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https://open.uns.ac.rs/handle/123456789/1787
Nаziv: | Candida bloodstream infections in Serbia: First multicentre report of a national prospective observational survey in intensive care units | Аutоri: | Valentina Arsić-Arsenijević Suzana Otašević Dragana Janić Predrag Minić Jovan Matijašević Deana Medić Ivanka Savić Snežana Delić Suzana Nestorović Laban Zorica Vasiljević Mirjana Hadnađev |
Ključnе rеči: | Candida bloodstream infections;intensive care unit;epidemiology;outcome;Serbia | Dаtum izdаvаnjа: | 1-феб-2018 | Čаsоpis: | Mycoses | Sažetak: | © 2017 Blackwell Verlag GmbH Candida bloodstream infections (BSI) are a significant cause of mortality in intensive care units (ICU), hereof the prospective 12-months (2014-2015) hospital- and laboratory-based survey was performed at the Serbian National Reference Medical Mycology Laboratory (NRMML). Candida identification was done by a matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry and a susceptibility test, according to the Clinical and Laboratory Standards Institute methodology. Among nine centres (265 beds; 10 820 patient admissions), four neonatal/paediatric (NICU/PICUs) and five adult centres (ICUs) participated, representing 89 beds and 3446 patient admissions, 166 beds and 7347 patient admissions respectively. The NRMML received 43 isolates, 17 from NICU/PICUs and 26 from adult ICUs. C. albicans dominated highly in NICU/PICUs (~71%), whereas C. albicans and C. parapsilosis were equally distributed within adults (46%, each), both accounting for ~90% of received isolates. The resistance to itraconazole and flucytosine were 25% and 2.4% respectively. In addition, the 2 C. albicans were azole cross-resistant (4.6%). The overall incidence of CandidaBSI was ~3.97 cases/1000 patient admissions (4.93 in NICU/PICU and 3.53 in adult ICU). The 30-day mortality was ~37%, most associated with C. tropicalis and C. glabrataBSI. Data from this national survey may contribute to improving the Balkan and Mediterranean region epidemiology of CandidaBSI within ICUs. | URI: | https://open.uns.ac.rs/handle/123456789/1787 | ISSN: | 9337407 | DOI: | 10.1111/myc.12700 |
Nаlаzi sе u kоlеkciјаmа: | MDF Publikacije/Publications |
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