1H NMR study of N–H⋯O hydrogen bonding – N-alkyl pivaloylamide–ketone (ether) systems

Abstract

The article reports the results of a 1H NMR study of a series of recently synthesized N-alkyl pivaloylamides in carbon tetrachloride solution and in presence of O-electron donors (acetone and tetrahydrofuran). Chemical shifts for free NH and NH · · · O bonded protons were obtained. Equilibrium constants for 1 : 1 amide-acetone/tetrahydrofuran hydrogen bonded complexes, at 25°C were determined.