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https://open.uns.ac.rs/handle/123456789/10977
Назив: | A comparative study of the lipophilicity of benzimidazole and benztriazole derivatives by RPTLC | Аутори: | Djaković-Sekulić T. Sârbu C. Perišić-Janjić N. |
Датум издавања: | 1-нов-2005 | Часопис: | Journal of Planar Chromatography - Modern TLC | Сажетак: | Chromatographic retention data RF and RM0 of some benzimidazole and benztriazole derivatives have been estimated by reversed-phase thin-layer chromatography on paraffin oil-impregnated silica gel plates with methanol-water mixtures as mobile phases. A quantitative structure-retention relationship (QSRR) correlation study was performed on a matrix containing retention data derived from chromatographic regression, retention scores provided by principal-components analysis (PCA), and different computed molecular descriptors. By means of multiple regression analysis statistically significant equations relating lipophilicity (estimated as RM0 values) to different descriptors were derived for the sixteen compounds. | URI: | https://open.uns.ac.rs/handle/123456789/10977 | ISSN: | 09334173 | DOI: | 10.1556/JPC.18.2005.6.6 |
Налази се у колекцијама: | TF Publikacije/Publications |
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