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https://open.uns.ac.rs/handle/123456789/10290
Title: | Inhibition by isoproterenol of the passive potassium efflux from pigeon erythrocytes | Authors: | Leskovac V. Peričin D. Trivić S. Stupar M. Murgul L. |
Issue Date: | 1-Jan-1984 | Journal: | Comparative Biochemistry and Physiology. Part C, Comparative | Abstract: | 1. Pigeon erythrocytes were carefully washed in an isotonic neutral buffer, devoid of potassium, and the rate of passive unidirectional efflux of potassium from the cells into a K+-free medium was measured after 20 min, at 40°C. 2. Isoproterenol inhibits K+-efflux by 35-45%, at a cell concentration of 1%; the isoproterenol effect is mediated by β-adrenergic receptors. 3. Cyclic AMP mimics the effect of isoproterenol, but at 4-5 orders of magnitude higher concentrations. 4. Cyclic AMP increases 20-fold the phosphorylation of purified cell membranes by [γ32P]ATP. © 1984. | URI: | https://open.uns.ac.rs/handle/123456789/10290 | ISSN: | 03064492 | DOI: | 10.1016/0742-8413(84)90117-8 |
Appears in Collections: | TF Publikacije/Publications |
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