Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/8727
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Summers T. | en_US |
dc.contributor.author | Langan R. | en_US |
dc.contributor.author | Nissan A. | en_US |
dc.contributor.author | Brücher B. | en_US |
dc.contributor.author | Bilchik A. | en_US |
dc.contributor.author | Mlađan Protić | en_US |
dc.contributor.author | Daumer M. | en_US |
dc.contributor.author | Avital I. | en_US |
dc.contributor.author | Stojadinović, Alexander | en_US |
dc.date.accessioned | 2019-09-30T09:10:43Z | - |
dc.date.available | 2019-09-30T09:10:43Z | - |
dc.date.issued | 2013-08-30 | - |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/8727 | - |
dc.description.abstract | Colorectal cancer (CRC) is the third most common cause of cancer-related death in the United States. Early identification and treatment of pre-cancerous colorectal lesions, or node-negative CRC are highly effective interventions that substantially reduce disease-specific mortality. Colonoscopy remains a highly effective primary screening tool based on its excellent diagnostic accuracy, and its ability to remove pre-cancerous lesions. However, the nature of the procedure limits compliance with colonoscopy intended for population-based CRC screening. A significant advance in the screening and care of these patients could be realized by blood-based biomarkers, which could accurately identify patients at-risk for CRC development whom might benefit from early and/or more frequent surveillance for disease. We reviewed and herein discuss the potential for serum based DNA methylation biomarkers for screening and early detection of CRC. ©Ivyspring International Publisher. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Journal of Cancer | en_US |
dc.subject | Biomarker | en_US |
dc.subject | Early detection | en_US |
dc.subject | Colorectal cancer | en_US |
dc.subject | DNA methylation | en_US |
dc.subject | Screening | en_US |
dc.subject | Serum | en_US |
dc.title | Serum-based DNA methylation biomarkers in colorectal cancer: Potential for screening and early detection | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.doi | 10.7150/jca.5839 | - |
dc.identifier.scopus | 2-s2.0-84880516297 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/84880516297 | - |
dc.description.version | Published | en_US |
dc.relation.lastpage | 216 | en_US |
dc.relation.firstpage | 210 | en_US |
dc.relation.issue | 3 | en_US |
dc.relation.volume | 4 | en_US |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Medicinski fakultet, Katedra za hirurgiju | - |
crisitem.author.parentorg | Medicinski fakultet | - |
Appears in Collections: | MDF Publikacije/Publications |
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