Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/851
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Aleksandar Rašković | en_US |
dc.contributor.author | Veljko Ćućuz | en_US |
dc.contributor.author | Ljilja Torović | en_US |
dc.contributor.author | Ana Tomas Petrović | en_US |
dc.contributor.author | Ljiljana Gojković-Bukarica | en_US |
dc.contributor.author | Tatjana Ćebović | en_US |
dc.contributor.author | Boris Milijašević | en_US |
dc.contributor.author | Nebojša Stilinović | en_US |
dc.contributor.author | Jelena Helen Hogervorst | en_US |
dc.date.accessioned | 2019-09-23T10:11:35Z | - |
dc.date.available | 2019-09-23T10:11:35Z | - |
dc.date.issued | 2019-01-01 | - |
dc.identifier.issn | 13190164 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/851 | - |
dc.description.abstract | © 2019 The Authors Resveratrol was recognized as the major factor responsible for the beneficial properties of red wine. Several resveratrol-based dietary supplements are available, but their efficacy has not been sufficiently tested. This study was designed to examine the effect of resveratrol supplementation, using a commercially available product, on the metabolic status of experimental animals with induced hyperlipidemia or type 2 diabetes mellitus (T2DM). Hyperlipidemia was induced by feeding the rats a standard pellet diet supplemented with cholesterol. T2DM was induced by adding 10% fructose to drinking water and streptozotocin. Treatment with resveratrol-based supplement improved glycemic control in diabetic animals and significantly decreased serum low-density-lipoprotein (LDL) and triglyceride levels, concurrently increasing the high-density-lipoprotein (HDL) levels in animals with hyperlipidemia. Resveratrol-treated animals had improved tolerance to glucose loading. Supplementation did not induce alterations in parameters of liver and renal function. Findings indicate that commercial resveratrol supplement improves metabolic control in rats with induced hyperlipidemia and T2DM. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Saudi Pharmaceutical Journal | en_US |
dc.subject | Resveratrol | en_US |
dc.subject | Diabetes | en_US |
dc.subject | Hyperlipidemia | en_US |
dc.subject | Metabolic parameters | en_US |
dc.title | Resveratrol supplementation improves metabolic control in rats with induced hyperlipidemia and type 2 diabetes | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.doi | 10.1016/j.jsps.2019.08.006 | - |
dc.identifier.scopus | 2-s2.0-85071844493 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85071844493 | - |
dc.description.version | Published | en_US |
dc.relation.lastpage | 1043 | en_US |
dc.relation.firstpage | 1036 | en_US |
dc.relation.issue | 7 | en_US |
dc.relation.volume | 27 | en_US |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Medicinski fakultet, Katedra za farmakologiju i toksikologiju | - |
crisitem.author.dept | Medicinski fakultet, Katedra za farmaciju | - |
crisitem.author.dept | Medicinski fakultet, Katedra za farmakologiju i toksikologiju | - |
crisitem.author.dept | Medicinski fakultet, Katedra za biohemiju | - |
crisitem.author.dept | Medicinski fakultet, Katedra za farmakologiju i toksikologiju | - |
crisitem.author.dept | Medicinski fakultet, Katedra za farmakologiju i toksikologiju | - |
crisitem.author.dept | Medicinski fakultet, Katedra za farmaciju | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
Appears in Collections: | MDF Publikacije/Publications |
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