Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/6827
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Danijela Jojkić Pavkov | en_US |
dc.contributor.author | Melanija Vislavski | en_US |
dc.contributor.author | Nada Vučković | en_US |
dc.contributor.author | Bojana Petrovački Dejanović | en_US |
dc.contributor.author | Matilda Djolai (Đolai) | en_US |
dc.contributor.author | Smiljana Marinković | en_US |
dc.contributor.author | Milena Mitrović | en_US |
dc.date.accessioned | 2019-09-30T08:57:45Z | - |
dc.date.available | 2019-09-30T08:57:45Z | - |
dc.date.issued | 2014-01-01 | - |
dc.identifier.issn | 13301403 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/6827 | - |
dc.description.abstract | Immaturity of ganglion cells is a rare form of dysganglionosis that belongs to the group of dysmorphic types, characterized by a normal or mildly decreased number of ganglion cells, with the cells and their nuclei being considerably smaller in size. The disorder usually manifests clinically early after birth with abdominal distension, vomiting, feeding intolerance, and delayed passing of meconium. Diagnostic evaluation may include radiological studies; however, biopsy of colonic mucosa with histochemical analysis is considered the most reliable method. Manometry is a reliable noninvasive diagnostic study to confi rm motility disorder. Treatment may be medical in mild cases and more commonly surgical due to complications of the disorder. We present a case of immature colonic ganglion cells as a cause of megacolon in infancy. In our case, medicamentous treatment was eff ective and led to normalization of bowel emptying and stool consistency. Considering that follow up rectosigmoidoscopy was refused by the patient's parents, we were not able to compare the histopathologic fi ndings before and after the medicamentous treatment; however, the favorable clinical course made us assume that the ganglion cells had probably fully matured. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Paediatria Croatica | en_US |
dc.subject | colon | en_US |
dc.subject | ganglia | en_US |
dc.subject | dygestive system abnormalities | en_US |
dc.subject | megacolon | en_US |
dc.subject | infant | en_US |
dc.title | Immature colonic ganglion cells as a cause of megacolon in infancy: Case report | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.doi | 10.13112/PC.2014.40 | - |
dc.identifier.scopus | 2-s2.0-84923093464 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/84923093464 | - |
dc.description.version | Published | en_US |
dc.relation.lastpage | 230 | en_US |
dc.relation.firstpage | 227 | en_US |
dc.relation.issue | 3 | en_US |
dc.relation.volume | 58 | en_US |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Medicinski fakultet, Katedra za patologiju | - |
crisitem.author.dept | Medicinski fakultet, Katedra za histologiju i embriologiju | - |
crisitem.author.dept | Medicinski fakultet, Katedra za internu medicinu | - |
crisitem.author.orcid | 0000-0002-8869-4806 | - |
crisitem.author.orcid | 0000-0001-9250-959x | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
Appears in Collections: | MDF Publikacije/Publications |
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