Please use this identifier to cite or link to this item: https://open.uns.ac.rs/handle/123456789/65
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dc.contributor.authorBranislava Srđenović Čonićen_US
dc.contributor.authorLjilja Torovićen_US
dc.contributor.authorNebojša Kladaren_US
dc.contributor.authorBiljana Božinen_US
dc.contributor.authorSuđi Janen_US
dc.date.accessioned2019-09-23T10:03:18Z-
dc.date.available2019-09-23T10:03:18Z-
dc.date.issued2019-10-01-
dc.identifier.issn2732300en_US
dc.identifier.urihttps://open.uns.ac.rs/handle/123456789/65-
dc.description.abstract© 2019 Elsevier Inc. In this study, 48 herbal based products (41 for the pediatric population) were analyzed for the presence of ethanol and residual solvents. Ethanol was not detected in only 12% of the products designed for infants or toddlers aged under 2, and not quantified in only 5 of 14 ‘alcohol free’ products. Actual content was higher than labeled in six out of 11 samples with specified ethanol quantity. WHO proposed requirement for ethanol content in products intended for use in children under the age of 6 (<0.5%) was not met by as many as 26 samples. Furthermore, calculated blood alcohol levels in children exceeded the relevant toxicological levels for nine samples following a single dose, and for one sample in case of accidental poisoning with the entire package. Regarding the residual solvents, acetone, 1-propanol and 1-butanol were not quantified, 2-propanol was found in two samples in low concentrations, whereas methanol intake via one of the samples exceeded the permitted level for children. The obtained results revealed a significant health concern for the pediatric population due to ethanol intake via herbal based products, calling for the establishment of strict guidelines for ethanol content and labeling.en_US
dc.language.isoenen_US
dc.relation.ispartofRegulatory Toxicology and Pharmacologyen_US
dc.subjectButanolen_US
dc.subjectPropanolen_US
dc.subjectAcetoneen_US
dc.subjectEthanolen_US
dc.subjectHSS-GC-MSen_US
dc.subjectHerbal productsen_US
dc.subjectMethanolen_US
dc.titleHealth risk assessment for pediatric population associated with ethanol and selected residual solvents in herbal based productsen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.doi10.1016/j.yrtph.2019.104406-
dc.identifier.pmid107-
dc.identifier.scopus2-s2.0-85067857401-
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/85067857401-
dc.description.versionPublisheden_US
dc.relation.volume107en_US
item.grantfulltextnone-
item.fulltextNo Fulltext-
crisitem.author.deptMedicinski fakultet, Katedra za farmaciju-
crisitem.author.deptMedicinski fakultet, Katedra za farmaciju-
crisitem.author.deptMedicinski fakultet, Katedra za farmaciju-
crisitem.author.deptMedicinski fakultet-
crisitem.author.orcid0000-0001-5781-6412-
crisitem.author.parentorgMedicinski fakultet-
crisitem.author.parentorgMedicinski fakultet-
crisitem.author.parentorgMedicinski fakultet-
crisitem.author.parentorgUniverzitet u Novom Sadu-
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