Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/6247
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jelena Radovanov | en_US |
dc.contributor.author | Vesna Milosevic | en_US |
dc.contributor.author | Ivana Hrnjaković Cvjetković | en_US |
dc.contributor.author | Mioljub Ristić | en_US |
dc.contributor.author | Milan Đilas | en_US |
dc.contributor.author | Nataša Nikolić | en_US |
dc.contributor.author | Aleksandra Patić | en_US |
dc.contributor.author | Gordana Kovačević | en_US |
dc.contributor.author | Aleksandra Jovanović-Galović | en_US |
dc.contributor.author | Tamaš Petrović | en_US |
dc.contributor.author | Sandra Stefan Mikić | en_US |
dc.date.accessioned | 2019-09-30T08:53:41Z | - |
dc.date.available | 2019-09-30T08:53:41Z | - |
dc.date.issued | 2015-01-01 | - |
dc.identifier.issn | 3708179 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/6247 | - |
dc.description.abstract | © 2015, Serbia Medical Society. All rights reserved. Introduction At present, two phylogenetically distinct influenza B virus lineages, B/Yamagata and B/ Victoria, co-circulate worldwide and can cause significant morbidity and mortality. Objective The aim of this study was to determine the prevalences of two influenza B virus lineages in the population of Vojvodina and to identify their antigenic and phylogenetic properties. Methods A total of 369 and 334 nasopharyngeal, or nasal/throat swab samples, collected during the 2012/2013 and 2013/2014 seasons, respectively, were tested using specific singleplex influenza A, influenza B, influenza B/Yamagata and influenza B/Victoria real-time reverse transcription polymerase chain reaction (RT-PCR) assays. Antigenic and genetic testing were done by hemagglutination inhibition assay and hemagglutinin and neuraminidase gene sequence analysis, respectively. Results During the 2012/2013 season, influenza B viruses were present in 53.4% (101/189) of influenza positive samples. The B/Yamagata-like viruses (81.2%) significantly predominated over the B/Victoria-like viruses (18.8%). Comparing to B/Victoria-like positive patients, among B/Yamagata-like positive patients, children 5–14 years of age were significantly more represented (5.3% vs. 35.4%, respectively), as well as patients with mild form of illness (15.8% vs. 45.1%, respectively). The results of sequence analysis and antigenic testing showed that tested viruses were not closely related to B/Wisconsin/1/2010, the vaccine virus for 2012/2013. During the 2013/2014 season influenza B viruses were not detected. Conclusion The results of this study confirmed the health significance of influenza B viruses and indicated that B/Yamagata-like viruses were significantly more prevalent than B/Victoria lineage viruses, during the 2012/2013 season. They also showed a sub-optimal match between the tested viruses and the vaccine virus for season 2012/2013. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Srpski Arhiv za Celokupno Lekarstvo | en_US |
dc.subject | influenza B | en_US |
dc.subject | acute respiratory infections | en_US |
dc.subject | epidemic | en_US |
dc.subject | real-time RT-PCR | en_US |
dc.title | Influenza B viruses in the population of province of vojvodina during the 2012/2013 Season: Differentiation of B/Yamagata and B/Victoria lineages by real-time RT-PCR, antigenic and phylogenetic characterization | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.doi | 10.2298/SARH1508429R | - |
dc.identifier.pmid | 143 | - |
dc.identifier.scopus | 2-s2.0-84941241619 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/84941241619 | - |
dc.description.version | Published | en_US |
dc.relation.lastpage | 437 | en_US |
dc.relation.firstpage | 429 | en_US |
dc.relation.issue | 7-8 | en_US |
dc.relation.volume | 143 | en_US |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Medicinski fakultet, Katedra za mikrobiologiju sa parazitologijom i imunologijom | - |
crisitem.author.dept | Medicinski fakultet, Katedra za epidemiologiju | - |
crisitem.author.dept | Medicinski fakultet, Katedra za mikrobiologiju sa parazitologijom i imunologijom | - |
crisitem.author.dept | Medicinski fakultet, Katedra za infektivne bolesti | - |
crisitem.author.orcid | 0000-0002-6923-189X | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
Appears in Collections: | MDF Publikacije/Publications |
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