Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/4863
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Pugalenthi A. | en_US |
dc.contributor.author | Mlađan Protić | en_US |
dc.contributor.author | Gonen M. | en_US |
dc.contributor.author | Kingham T. | en_US |
dc.contributor.author | Angelica M. | en_US |
dc.contributor.author | Dematteo R. | en_US |
dc.contributor.author | Fong Y. | en_US |
dc.contributor.author | Jarnagin W. | en_US |
dc.contributor.author | Allen P. | en_US |
dc.date.accessioned | 2019-09-30T08:42:48Z | - |
dc.date.available | 2019-09-30T08:42:48Z | - |
dc.date.issued | 2016-02-01 | - |
dc.identifier.issn | 224790 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/4863 | - |
dc.description.abstract | © 2015 Wiley Periodicals, Inc. Introduction Pancreaticoduodenectomy (PD) performed for pancreatic ductal adenocarcinoma (PDA) has a postoperative morbidity of 40-50%. In this study, we analyzed the impact of high grade complications after PD for PDA on overall survival. Methods A total of 596 patients that underwent PD for PDA between 2001 and 2009 were identified from a prospective database. Complications were defined and graded (1-5) as per our Institutional Surgical Secondary Events Program. High grade complications were defined as ≥grade 3. Postoperative mortality (≤90 days) was excluded. Univariate and multivariate analyses were performed to identify factors associated with overall survival. Results Median survival was 24 months. Overall complication rate was 51% (301/596). Low grade complications were recorded in 266 patients (45%) and high grade complications in 22% (n = 129). Our 90 day mortality was 3.7% (n = 22). Anastomotic fistula/leak/abscess rate was 14% (n = 82). Multivariate Cox-Regression analysis identified node positivity, estimated blood loss (EBL) >600 ml, length of stay (LOS) >10 days, margin positivity, and vascular procedures as predictors of decreased overall survival (P < 0.05). High grade complications were not associated with overall survival (P = 0.948). Conclusion In this study, the occurrence of high grade postoperative complications was not associated with overall survival. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Journal of Surgical Oncology | en_US |
dc.subject | complications | en_US |
dc.subject | pancreatic ductal adenocarcinoma | en_US |
dc.subject | pancreaticoduodenectomy | en_US |
dc.subject | survival | en_US |
dc.title | Postoperative complications and overall survival after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.doi | 10.1002/jso.24125 | - |
dc.identifier.pmid | 113 | - |
dc.identifier.scopus | 2-s2.0-84957850494 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/84957850494 | - |
dc.description.version | Published | en_US |
dc.relation.lastpage | 193 | en_US |
dc.relation.firstpage | 188 | en_US |
dc.relation.issue | 2 | en_US |
dc.relation.volume | 113 | en_US |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Medicinski fakultet, Katedra za hirurgiju | - |
crisitem.author.parentorg | Medicinski fakultet | - |
Appears in Collections: | MDF Publikacije/Publications |
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