Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/28232| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | Đurendić Evgenija | - |
| dc.contributor.author | Savić Marina P. | - |
| dc.contributor.other | Penov-Gaši Katarina | - |
| dc.contributor.other | Sakač Marija | - |
| dc.contributor.other | Csanádi János | - |
| dc.contributor.other | Djilas Sonja | - |
| dc.date.accessioned | 2020-12-13T23:01:02Z | - |
| dc.date.available | 2020-12-13T23:01:02Z | - |
| dc.date.issued | 2013-03-19 | - |
| dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/28232 | - |
| dc.description.abstract | <p>U prvom delu ove doktorske disertacije je izvršena<br />sinteza novih derivata androstana sa D-laktonskom<br />funkcijom ili D-seko derivata, sa modifikacijama u Ai/<br />ili B-prstenovima. U drugom delu je ispitana<br />antiproliferativna aktivnost odabranih<br />novosintetizovanih jedinjenja prema humanim<br />tumorskim ćelijskim linijama (MCF-7, MDA-MB-231,<br />PC-3, HeLa, HT-29, K562) kao i prema zdravim<br />ćelijama fetalnih fibroblasta pluća (MRC-5).</p> | sr |
| dc.description.abstract | <p>In first part of this work was achieved synthesis of some new androstane derivatives with D-lactone function and new D-seco derivatives with modification in A and/or B rings. In the second part the antiproliferative activity of selected newly synthesized compounds by human carcinoma cell lines (MCF-7, MDA-MB-231, PC-3, HeLa, HT-29, K562) and the healthy cells of fetal lung fibroblasts (MRC-5 ) was examined.</p> | en |
| dc.format.mimetype | application/pdf | - |
| dc.language.iso | sr (latin script) | - |
| dc.publisher | Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu | sr |
| dc.publisher | University of Novi Sad, Faculty of Sciences at Novi Sad | en |
| dc.source | CRIS UNS | - |
| dc.source.uri | http://cris.uns.ac.rs | - |
| dc.subject | Synthesis, steroids, androstane derivatives, antiproliferative activity | en |
| dc.subject | Sinteza, steroidi, derivati androstana, antiproliferativna aktivnost | sr |
| dc.title | Synthesis and antiproliferative activity of new D-homo and D-seco androstane derivatives | en |
| dc.title | Sinteza i antiproliferativna aktivnost novih D-homo i D-seko derivata androstana | sr |
| dc.type | Thesis | en |
| dc.identifier.doi | 10.2298/NS20130319SAVIC | - |
| dc.identifier.url | https://www.cris.uns.ac.rs/DownloadFileServlet/DisertacijaSinteza%20i%20antiproliferativna%20aktivnost%20novih%20D-homo%20i%20D-seko%20derivata%20androstana.pdf?controlNumber=(BISIS)82689&fileName=Sinteza%20i%20antiproliferativna%20aktivnost%20novih%20D-homo%20i%20D-seko%20derivata%20androstana.pdf&id=552&source=BEOPEN&language=en | en |
| dc.identifier.url | https://www.cris.uns.ac.rs/record.jsf?recordId=82689&source=BEOPEN&language=en | en |
| dc.identifier.externalcrisreference | (BISIS)82689 | - |
| dc.source.institution | Prirodno-matematički fakultet u Novom Sadu | sr |
| item.grantfulltext | none | - |
| item.fulltext | No Fulltext | - |
| Appears in Collections: | PMF Teze/Theses | |
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