Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/268
DC Field | Value | Language |
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dc.contributor.author | Al Fazazi, S. | en_US |
dc.contributor.author | Štajer, Valdemar | en_US |
dc.contributor.author | Drid, Patrik | en_US |
dc.contributor.author | Maksimović, Nebojša | en_US |
dc.contributor.author | Milošević, Zoran | en_US |
dc.contributor.author | Ostojić, Sergej | en_US |
dc.date.accessioned | 2019-09-23T10:05:36Z | - |
dc.date.available | 2019-09-23T10:05:36Z | - |
dc.date.issued | 2019-06 | - |
dc.identifier.issn | 7651597 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/268 | - |
dc.description.abstract | Introduction: Exhaustive exercise adversely affects biomarkers of creatine metabolism yet it remains unknown when the values back toward pre-disturbance conditions. Here, we evaluated a 24-hour post-exercise response in serum guanidinoacetic acid (GAA), creatine and creatinine in young active men subjected to a single session of exhaustive resistance exercise and matched it with exercise-induced changes in serum cortisol, interleukin 6 (IL-6), creatine kinase (CK), and lactate dehydrogenase (LDH). Summary of facts and results: Twelve healthy active men (age 22.7 ± 0.8 years; weight 79.8 ± 7.3 kg; height 182.4 ± 4.9 cm; weekly exercise 5.1 ± 1.6 hours) were subjected to a single session of bench press exercise until volitional exhaustion, with venous blood sampled before, immediately after exercise (∼ 2 min), and after 15 min, 60 min and 24 h after the end of exercise. Baseline values for serum GAA, creatine and creatinine were 2.2 ± 0.5 μmol/L, 18.9 ± 3.6 μmol/L, and 72.4 ± 6.0 μmol/L, respectively. Serum GAA significantly dropped for 9.6 ± 7.3% immediately after bench press exercise (95% CI, 5.0 to 14.2; P < 0.001), while both creatine and creatinine increased immediately after the test for 5.0 ± 2.5% (95% CI, 3.4 to 6.6; P < 0.001) and 11.9 ± 4.3% (95% CI, 9.2 to 14.6; P < 0.001), respectively. GAA and creatine levels recovered to the baseline values after 24 hours post-exercise, yet creatinine remained significantly higher at 24-hour period as compared to the baseline values for 2.5 ± 2.3% (95% CI, 1.0 to 4.0; P = 0.002). In addition, no significant correlations were found between serum cortisol, IL-6, CK and LDH and creatine metabolites (P > 0.05). Conclusion: A single session of exhaustive resistance exercise induces transient alterations in biomarkers of creatine metabolism, with serum creatinine outlined as a most persistent marker of exhaustion. Exercise-induced changes in creatine metabolism poorly corresponded to perturbations in inflammation and muscle fatigue biomarkers following exercise. © 2018 Elsevier Masson SAS. All rights reserved. | en_US |
dc.relation.ispartof | Science and Sports | en_US |
dc.title | 24-hour dynamics for serum biomarkers of creatine metabolism after an acute session of exhaustive resistance exercise in active men | en_US |
dc.type | Other | en_US |
dc.identifier.doi | 10.1016/j.scispo.2018.12.001 | - |
dc.identifier.scopus | 2-s2.0-85058617052 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85058617052 | - |
dc.description.version | Unknown | en_US |
dc.relation.lastpage | 185 | en_US |
dc.relation.firstpage | 181 | en_US |
dc.relation.issue | 3 | en_US |
dc.relation.volume | 34 | en_US |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Кatedra za fizičko i zdravstveno vaspitanje | - |
crisitem.author.dept | Кatedra za individualne sportove | - |
crisitem.author.dept | Кatedra za primenjene sportske nauke | - |
crisitem.author.dept | Кatedra za fizičko i zdravstveno vaspitanje | - |
crisitem.author.dept | Кatedra za primenjene sportske nauke | - |
crisitem.author.orcid | 0000-0002-4000-7624 | - |
crisitem.author.orcid | 0000-0003-3279-4098 | - |
crisitem.author.orcid | 0000-0001-7408-2545 | - |
crisitem.author.orcid | 0000-0002-7270-2541 | - |
crisitem.author.parentorg | Fakultet sporta i fizičkog vaspitanja | - |
crisitem.author.parentorg | Fakultet sporta i fizičkog vaspitanja | - |
crisitem.author.parentorg | Fakultet sporta i fizičkog vaspitanja | - |
crisitem.author.parentorg | Fakultet sporta i fizičkog vaspitanja | - |
crisitem.author.parentorg | Fakultet sporta i fizičkog vaspitanja | - |
Appears in Collections: | FSFV Publikacije/Publications |
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