Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/18628
DC Field | Value | Language |
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dc.contributor.author | Bogavac Mirjana | - |
dc.contributor.author | Jakovljević Ana | - |
dc.contributor.author | Stajić Zoran | - |
dc.contributor.author | Nikolić Aleksandra | - |
dc.contributor.author | Milošević-Tošić Mirjana | - |
dc.contributor.author | Dejanović Jadranka | - |
dc.contributor.author | Lozanov-Crvenković Zagorka | - |
dc.date.accessioned | 2020-12-13T12:55:00Z | - |
dc.date.available | 2020-12-13T12:55:00Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0042-8450 | - |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/18628 | - |
dc.description.abstract | © 2017, Institut za Vojnomedicinske Naucne Informacije/Documentaciju. All rights reserved. Background/Aim. Preeclampsia (PE) is a multisystemic syndrome that complicates 5-8% of all pregnancies. The aim of this study was to evaluate the biochemical parameters of oxidative stress in the first trimester of pregnancy in patients with preeclampsia, with the purpose of comparing the level of oxidative stress with normal pregnancy. Methods. The study was conducted as a prospective study. It included totally 107 pregnant women divided into two groups. In the study group (n = 33) there were women who developed preeclampsia in the current pregnancy. The control group (n = 74) included healthy pregnant women. Blood samples were taken between 11th and 14th weeks of gestation, and the values of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and total antioxidant status (TAS) were determined in serum by enzymatic colorimetric methods. Results. The values of SOD and GHS-Px were statistically higher in the study group, while the values of TAS were statistically higher in the control group. The level of TAS inversely correlated with GSH-Px and SOD, but there is no statistically significant correlation between GSHPx and SOD in the study group. Conclusion. The results of this study suggest a higher level of oxidative stress in the first trimester of pregnancy with preeclampsia, which may indicate that the initiation and development of pathophysiological processes underlying preeclampsia start much earlier than the clinical syndrome exhibit. | - |
dc.language.iso | en | - |
dc.relation.ispartof | Vojnosanitetski Pregled | - |
dc.source | CRIS UNS | - |
dc.source.uri | http://cris.uns.ac.rs | - |
dc.subject | oxidative stress | - |
dc.subject | preeclampsia | - |
dc.subject | first trimester | - |
dc.title | Preeclampsia and level of oxidative stress in the first trimester of pregnancy | - |
dc.type | Journal/Magazine Article | - |
dc.identifier.doi | 10.2298/VSP150517251B | - |
dc.identifier.scopus | 2-s2.0-85023638304 | - |
dc.identifier.url | https://www.cris.uns.ac.rs/record.jsf?recordId=107408&source=BEOPEN&language=en | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85023638304 | - |
dc.description.version | Published | - |
dc.relation.lastpage | 638 | - |
dc.relation.firstpage | 633 | - |
dc.relation.issue | 7 | - |
dc.relation.volume | 74 | - |
dc.identifier.externalcrisreference | (BISIS)107408 | - |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Medicinski fakultet, Katedra za ginekologiju i akušerstvo | - |
crisitem.author.dept | Medicinski fakultet, Katedra za patološku fiziologiju i laboratorijsku medicinu | - |
crisitem.author.dept | Medicinski fakultet, Katedra za farmaciju | - |
crisitem.author.dept | Prirodno-matematički fakultet, Departman za matematiku i informatiku | - |
crisitem.author.orcid | 0000-0002-2967-3060 | - |
crisitem.author.orcid | 0000-0003-2426-9197 | - |
crisitem.author.orcid | 0000-0002-6188-2348 | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Prirodno-matematički fakultet | - |
Appears in Collections: | MDF Publikacije/Publications |
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