Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/1475
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Velibor Čabarkapa | en_US |
dc.contributor.author | Mirjana Bogavac | en_US |
dc.contributor.author | Ana Jakovljević | en_US |
dc.contributor.author | Lato Pezo | en_US |
dc.contributor.author | Aleksandra Nikolić | en_US |
dc.contributor.author | Zoran Belopavlović | en_US |
dc.contributor.author | Mirjana Đerić | en_US |
dc.date.accessioned | 2019-09-23T10:15:51Z | - |
dc.date.available | 2019-09-23T10:15:51Z | - |
dc.date.issued | 2018-07-03 | - |
dc.identifier.issn | 10641955 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/1475 | - |
dc.description.abstract | © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. Objectives: The aim of this study was to evaluate the importance of serum concentration of magnesium (Mg) in the first trimester of pregnancy for predicting pre-eclampsia (PE). Methods: This prospective study included 403 pregnant women over 18, with singleton pregnancy (from 11 to 14 weeks of pregnancy). The subjects were divided into a group who subsequently developed PE (PEKT) (n = 61), and a group of healthy pregnancies with no complications and with normal outcomes (TNT) (n = 342). In the first trimester, urea, creatinine, uric acid, Mg, free beta subunit of human chorionic gonadotrophin, plasma protein A related to pregnancy, and C-reactive protein were determined. We followed all subjects until the end of pregnancy. Results: Serum Mg is significantly lower in PEKT than in TNT group (p < 0.001). The serum first trimester Mg level cutoff at ≤0.81 mmol/L had a sensitivity of 77.0% and specificity of 71.6% for the detection of women with PEKT. The level of serum Mg has the strongest significant positive correlation (p < 0.05) with the week of gestational outcomes (R = 0.442), weight (R = 0.416), and Apgar score (R = 0.343) of the newborns, and the strongest significant negative correlation with the number of miscarriages (R = −0.413), serum creatinine (R = −0.471), and the number of pregnancies (R = −0.326). The week of gestational outcome is predicted with the greatest reliability by the serum Mg. Conclusions: Serum Mg level during the first trimester of pregnancy is a significant prediction tool for PE and could also play an important role in predicting the week of gestational outcome and birth weight of newborns. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Hypertension in Pregnancy | en_US |
dc.subject | Assesment | en_US |
dc.subject | magnesium | en_US |
dc.subject | normal pregnancy | en_US |
dc.subject | nutrition | en_US |
dc.subject | pre-eclampsia | en_US |
dc.title | Serum magnesium level in the first trimester of pregnancy as a predictor of pre-eclampsia–a pilot study | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.doi | 10.1080/10641955.2018.1494189 | - |
dc.identifier.pmid | 37 | - |
dc.identifier.scopus | 2-s2.0-85050384165 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85050384165 | - |
dc.description.version | Published | en_US |
dc.relation.lastpage | 153 | en_US |
dc.relation.firstpage | 144 | en_US |
dc.relation.issue | 3 | en_US |
dc.relation.volume | 37 | en_US |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Medicinski fakultet, Katedra za patološku fiziologiju i laboratorijsku medicinu | - |
crisitem.author.dept | Medicinski fakultet, Katedra za ginekologiju i akušerstvo | - |
crisitem.author.dept | Medicinski fakultet, Katedra za patološku fiziologiju i laboratorijsku medicinu | - |
crisitem.author.dept | Medicinski fakultet, Katedra za farmaciju | - |
crisitem.author.orcid | 0000-0002-2967-3060 | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
Appears in Collections: | MDF Publikacije/Publications |
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