Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/14191
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Sonja Salinger-Martinović | en_US |
dc.contributor.author | Zorica Dimitrijević | en_US |
dc.contributor.author | Dragana Stanojević | en_US |
dc.contributor.author | Stefan Momčilović | en_US |
dc.contributor.author | Tomislav Kostić | en_US |
dc.contributor.author | Goran Koračević | en_US |
dc.contributor.author | Bojana Subotić | en_US |
dc.contributor.author | Boris Džudović | en_US |
dc.contributor.author | Branislav Stefanović | en_US |
dc.contributor.author | Jovan Matijašević | en_US |
dc.contributor.author | Milica Mirić | en_US |
dc.contributor.author | Nataša Marković-Nikolić | en_US |
dc.contributor.author | Maja Nikolić | en_US |
dc.contributor.author | Vladimir Miloradović | en_US |
dc.contributor.author | Ljiljana Kos | en_US |
dc.contributor.author | Tamara Kovačević-Preradović | en_US |
dc.contributor.author | Ilija Srdanović | en_US |
dc.contributor.author | Jelena Stanojev | en_US |
dc.contributor.author | Slobodan Obradović | en_US |
dc.date.accessioned | 2020-03-03T14:55:17Z | - |
dc.date.available | 2020-03-03T14:55:17Z | - |
dc.date.issued | 2019-01-01 | - |
dc.identifier.issn | 1675273 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/14191 | - |
dc.description.abstract | © 2019 Background: Acute pulmonary embolism (PE), due to hemodynamic disturbances, may lead to multi-organ damage, including acute renal dysfunction. The aim of our study was to investigate the predictive role of renal dysfunction at admission regarding the short-term mortality and bleeding risk in hospitalized PE patients. Methods: The retrospective cohort study included 1330 consecutive patients with PE. The glomerular filtration rate (GFR) was calculated using the serum creatinine value and Cocroft-Gault formula, at hospital admission. Primary outcomes were all-cause mortality and PE-related mortality in the 30 days following admission, as well as major bleeding events. Results: Based on the estimated GFR, patients were divided into three groups: the first with GFR < 30 mL/min, the second with GFR 30–60 mL/min, and the third group with GFR > 60 mL/min. A multivariable analysis showed that GFR at admission was strongly associated with all-cause death, as well as with death due to PE. Patients in the first and second group had a significantly higher risk of 30-day all-cause mortality (HR 7.109, 95% CI 4.243–11.911, p < 0.001; HR 2.554, 95% CI 1.598–4.081, p < 0.001). Fatal bleeding was recorded in 1.6%, 0.5% and 0.8% of patients in the first, second and in the third group (p < 0.05). There were no significant differences regarding major bleeding rates among the groups. Conclusion: Renal dysfunction at admission in patients with acute pulmonary embolism is strongly associated with overall PE mortality. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | International Journal of Cardiology | en_US |
dc.subject | Bleeding | en_US |
dc.subject | Pulmonary embolism | en_US |
dc.subject | Renal dysfunction | en_US |
dc.subject | Prognosis | en_US |
dc.title | Renal dysfunction as intrahospital prognostic indicator in acute pulmonary embolism | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.doi | 10.1016/j.ijcard.2019.12.025 | - |
dc.identifier.scopus | 2-s2.0-85076826149 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85076826149 | - |
dc.description.version | Published | en_US |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Medicinski fakultet, Katedra za zdravstvenu negu | - |
crisitem.author.dept | Medicinski fakultet, Katedra za urgentnu medicinu | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
Appears in Collections: | MDF Publikacije/Publications |
SCOPUSTM
Citations
3
checked on Nov 20, 2023
Page view(s)
27
Last Week
8
8
Last month
2
2
checked on May 10, 2024
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.