Selectivity in a liquid-solid chromatographic system

Abstract

Utilizing experimentally determined capacity ratios and "a priori" calculated activity coefficients of the solutes the selectivity of separation in a liquid-solid chromatographic system is studied. Both the experimentally determined selectivity factor (α) and the calculated selectivity factor in the mobile phase (α m) of a solute pair fit a quadratic function of the concentration of eluting solvent components. Comparing these factors it is shown that the selectivity in the stationary phase (α s) is fairly constant when the composition of the mobile phase is changed. © 1987 Friedr. Vieweg & Sohn Verlagsgesellschaft mbH.