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https://open.uns.ac.rs/handle/123456789/12359
Поље DC-а | Вредност | Језик |
---|---|---|
dc.contributor.author | Tatjana Šarčev | en_US |
dc.contributor.author | Nevena Sečen | en_US |
dc.contributor.author | Đorđe Považan | en_US |
dc.contributor.author | Ana Sabo | en_US |
dc.contributor.author | Jovan Popović | en_US |
dc.contributor.author | Daliborka Bursać | en_US |
dc.contributor.author | M. Kakas | en_US |
dc.contributor.author | Bojan Zarić | en_US |
dc.contributor.author | A. Milovančev | en_US |
dc.date.accessioned | 2020-03-03T14:48:12Z | - |
dc.date.available | 2020-03-03T14:48:12Z | - |
dc.date.issued | 2007-04-01 | - |
dc.identifier.issn | 11070625 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/12359 | - |
dc.description.abstract | Purpose: The aim of this study was to determine the influence of dexamethasone in the decrease of cisplatin and etoposide-induced nausea and vomiting inpatients treated for lung cancer during and after 2 chemotherapy cycles. Patients and methods: The analysis included 60 patients with histologically proven lung cancer, who were divided in two groups. Group A consisted of 30 patients who received cisplatin and etoposide with standard antiemetic drugs: ondansetron [serotonin receptor antagonist (5-HT3 antagonist)] and metoclopramide (dopamine receptor antagonist). Group B consisted of 30 patients who received the same chemotherapy regimen with the previous antiemetic therapy plus dexamethasone 8 mg intravenously (i.v.) per day during the 3 days of chemotherapy. During and after the 3-day therapy, patients filled in a questionnaire issuing adverse effects of chemotherapy concerning many symptoms including nausea and vomiting. The results were statistically processed. Results: There was a significant decrease in the frequency and toxicity of nausea, acute and delayed vomiting in the group of patients who received antiemetic treatment with ondansetron, metoclopramide plus dexamethasone. Conclusion: Dexamethasone administered with 5-HT3 antagonists and dopamine receptor antagonists significantly decreases the chemotherapy-induced nausea and vomiting. © 2007 Zerbinis Medical Publications. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Journal of B.U.ON. | en_US |
dc.subject | antiemetic treatment | en_US |
dc.subject | chemotherapy | en_US |
dc.subject | dexamethasone | en_US |
dc.subject | lung cancer | en_US |
dc.subject | nausea | en_US |
dc.subject | vomiting | en_US |
dc.title | The influence of dexamethasone in the decrease of chemotherapy-induced nausea and vomiting | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.pmid | 12 | - |
dc.identifier.scopus | 2-s2.0-34447137046 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/34447137046 | - |
dc.description.version | Published | en_US |
dc.relation.lastpage | 252 | en_US |
dc.relation.firstpage | 245 | en_US |
dc.relation.issue | 2 | en_US |
dc.relation.volume | 12 | en_US |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Katedra za internu medicinu | - |
crisitem.author.dept | Katedra za internu medicinu | - |
crisitem.author.dept | Katedra za internu medicinu | - |
crisitem.author.dept | Katedra za internu medicinu | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
Налази се у колекцијама: | MDF Publikacije/Publications |
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