Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/11933
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Đaković-Sekulić, Tatjana | en_US |
dc.contributor.author | Perišić-Janjić N. | en_US |
dc.contributor.author | Djurendi E. | en_US |
dc.date.accessioned | 2020-03-03T14:46:32Z | - |
dc.date.available | 2020-03-03T14:46:32Z | - |
dc.date.issued | 2009-10-05 | - |
dc.identifier.issn | 02693879 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/11933 | - |
dc.description.abstract | The chromatographic behaviour of salicylic acid derivatives was investigated using reversed-phase high performance thin-layer chromatography (RP HPTLC) with methanol-water and dioxane-water binary mixtures as mobile phase in order to establish relationships between chromatographic data and selected physico-chemical parameters that are related to ADME (absorption, distribution, metabolism and elimination). Some of the investigated compounds were screened for antioxidant activity. Examination of chromatographic behaviour revealed a linear correlation between RM values and the volume fraction of mobile phase modifier. Obtained RM0 values were correlated with lipophilicity, solubility, human intestinal absorption, plasma-protein binding, and blood-brain barrier data. The comparison among chromatographic data obtained by two mobile phase was performed with a statistical technique, principle component analysis. Copyright © 2009 John Wiley & Sons, Ltd. | en |
dc.relation.ispartof | Biomedical Chromatography | en |
dc.title | Retention data from reverse-phase high-performance thin-layer chromatography in characterization of some bis-salicylic acid derivatives | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.doi | 10.1002/bmc.1200 | - |
dc.identifier.pmid | 23 | - |
dc.identifier.scopus | 2-s2.0-70349503836 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/70349503836 | - |
dc.description.version | Unknown | en_US |
dc.relation.lastpage | 887 | en |
dc.relation.firstpage | 881 | en |
dc.relation.issue | 8 | en |
dc.relation.volume | 23 | en |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
crisitem.author.dept | Departman za hemiju, biohemiju i zaštitu životne sredine | - |
crisitem.author.orcid | 0000-0002-4333-9085 | - |
crisitem.author.parentorg | Prirodno-matematički fakultet | - |
Appears in Collections: | PMF Publikacije/Publications |
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