Please use this identifier to cite or link to this item:
https://open.uns.ac.rs/handle/123456789/10008
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jasminka Marković | en_US |
dc.contributor.author | Tijana Momčilov-Popin | en_US |
dc.contributor.author | Dragan Mitrović | en_US |
dc.contributor.author | Svetlana Ivanović Kovačević | en_US |
dc.contributor.author | Slobodan Sekulić | en_US |
dc.contributor.author | Anastazija Stojšić Milosavljević | en_US |
dc.date.accessioned | 2020-03-03T14:36:37Z | - |
dc.date.available | 2020-03-03T14:36:37Z | - |
dc.date.issued | 2011-10-18 | - |
dc.identifier.issn | 19948220 | en_US |
dc.identifier.uri | https://open.uns.ac.rs/handle/123456789/10008 | - |
dc.description.abstract | Objective: To report a case of a patient treated with clozapine who developed pericarditis with pericardial effusion that resolved when the drug was discontinued. Method: Case report of a 21-year-old man with psychotic disorder that had been stable on clozapine therapy for five months (after failure of atypical antipsyhotic agents) presented to the emergency department complaining of chest pain and progressive shortness of breath that had lasted for a few days. Echocardiography showed a pericardial effusion suggestive of a cardiac tamponade, and the fluid was removed by pericardiocentesis. All other possible causes of the pericardial effusion were ruled out and clozapine was suspected as the most likely explanation. Clozapine was discontinued and the patient's symptoms improved markedly. Discussion: According to the Naranjo probability scale, clozapine is a probable cause of pericarditis. Although clozapine is a known cause of myocarditis and cardiomyopathy, there are only several reports in the literature describing clozapine-induced pericarditis and pericardial effusion. In our patient, the pericardial effusion cleared within several days following clozapine discontinuation. Conclusion: There have been only a few cases of clozapine-induced pericarditis reported in the literature, however this adverse effect of clozapine can occur, as this case report clearly demonstrates. Cardiac adverse effects of clozapine are potentially life threatening, hence early recognition is essential to prevent serious outcomes. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | African Journal of Psychiatry (South Africa) | en_US |
dc.subject | Clozapine | en_US |
dc.subject | Pericarditis | en_US |
dc.subject | Pericardial effusion | en_US |
dc.subject | Adverse reaction | en_US |
dc.title | Clozapine-induced pericarditis | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.doi | 10.4314/ajpsy.v14i3.7 | - |
dc.identifier.pmid | 14 | - |
dc.identifier.scopus | 2-s2.0-80054033609 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/80054033609 | - |
dc.description.version | Published | en_US |
dc.relation.lastpage | 238 | en_US |
dc.relation.firstpage | 236 | en_US |
dc.relation.issue | 3 | en_US |
dc.relation.volume | 14 | en_US |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Katedra za psihijatriju i medicinsku psihologiju | - |
crisitem.author.dept | Katedra za neurologiju | - |
crisitem.author.dept | Katedra za internu medicinu | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
crisitem.author.parentorg | Medicinski fakultet | - |
Appears in Collections: | MDF Publikacije/Publications |
SCOPUSTM
Citations
22
checked on May 3, 2024
Page view(s)
49
Last Week
13
13
Last month
0
0
checked on May 3, 2024
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.